How to Use Synthesis Plural (Explained, With Examples)

August 6, 2025
5 min read
By Yash, D

Synthesis (noun) is the combining of ideas to form a theory or system. In science, synthesis refers to chemical compounds produced by basic elements.

How to Use Synthesis Plural (Explained, With Examples)

Is synthesis singular or plural?

What’s with the word synthesis, and why does it behave the way it does from its singular to plural form? Keep reading.

👍🏼 Examples: synthesis vs. syntheses
âś“ He describes his latest record as "a synthesis of African and Latin rhythms".
âś“ In different seeds, the syntheses of the enzymes occur in different areas.
  • Synthesis (pronounced SIN-thuh-siss)is singular.
  • Syntheses (pronounced sin·thuh·seaz) is plural.

The meaning of synthesis

The Merriam-Webster defines the word synthesis as “the composition or combination of parts or elements so as to form a whole.”

What’s the plural of synthesis?

The plural of synthesis (i.e., syntheses), is irregular. While it ends in –es as a plural (and, in this sense, follows the regular plural noun form), it does so by replacing its suffix as a singular noun. This is unusual in English grammar. Typically, to form a plural, you would add the -es/-s: books, phones, dogs and cats all form a plural by adding an s to demonstrate plurality. It’s an easy, simple, and straightforward way to form a plural noun—just add the s.

This rule of pluralization doesn’t work in the case of synthesis, hypothesis, thesis, synopsis, crisis, oasis,  diagnosis (the list goes on). Each of these nouns/words were introduced to Modern English from the Greek; “a synthesis,” comes from Greek Greek synthesis “composition, a putting together,” from syntithenai “put together, combine,” from syn- “together”. These irregular, Greek words all modify the same way from singular to plural. See the chart below.

English's Greek Plural (ending in -sis & -ses)

Singular Plural
crisis crises
diagnosis diagnoses
oasis oases
synopsis synopses
Greek nouns in English

Example sentences: synthesis & syntheses

Noun: synthesis Example sentences
synthesis

This kind of lighting encourages vitamin D synthesis in the skin.

There are procedures for the synthesis or organic compounds from elements.

The vitamin participates in the human body’s synthesis of proteins for cellular growth .

syntheses

The syntheses and other testing are forthcoming.

The project involved multiple syntheses of complex peptides to achieve the desired quantity.

The research paper presented three different syntheses of the same compound, each with its own advantages.

Quotes from the media & literature

Analysis and synthesis are expected to occur within the expanded talk as well as the abbreviated talk.

—J. Fienberg & G. Leinhardt, Learning Conversations in Museums

Deduction is synthesis when it is progressive from real ground to consequence.

—Encyclopædia Britannica, 1911

For Marx..the manner of synthesis depends..upon the shifts and realignments of human interests in time.

S. Hook—From Hegel to Marx, 1936

M. Berthelot..made the first successful attempt to perform organic syntheses. On Fermentation, 1876

translation of P. Schützenberger—On Fermentation, 1876

Synonyms & nearby words

Synonyms for synthesis/syntheses

admixture amalgamation combination conflation alloy composite mixture meld blend fusion integration coalescence

Sources

  1. Soulsby, B. H., and Elizabeth Baigent. "Richardson, John (1797–1852), author." Oxford Dictionary of National Biography. September 23, 2004. Oxford University Press. Date of access 7 Sep. 2025.
  2. “Amalgamation, N.” Oxford English Dictionary, Oxford UP, March 2025, https://doi.org/10.1093/OED/6892473758.

Yash, D. "How to Use Synthesis Plural (Explained, With Examples)." Grammarflex, Sep 27, 2025, https://grammarflex.com/synthesis-plural/.

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